This week we are covering simple inheritance. You will discuss the article Mendelian Genetics: Patterns of Inheritance and Single-Gene DisordersLinks to an external site. by Heidi Chial. She explains that some human diseases that follow a pattern of inheritance that follows Mendel’s monozygotic genetics are known as single gene disorders. However, there are also plenty of single gene phenotypes in humans, that may not really be determined by just one gene. So, in your discussion, include information you gain from browsing the Myth of Human GeneticsLinks to an external site. site discussing textbook examples of assumed single gene heredity of non-disease traits (physical appearance and behavior).
post discussion and contribute response to the following discussion
Hello class, after reading Heidi Chial’s article “Mendelian Genetics: Patterns of Inheritance and Single-Gene Disorders” we see that is goes over how certain human diseases adhere to Mendelian genetics, exhibiting patterns of inheritance known as single gene disorders. These disorders come from mutations in individual genes and typically can be predictable inheritance patterns, such as autosomal dominant, autosomal recessive, or X-linked inheritance.
However, not all human phenotypes ascribed to single genes are as straightforward. The Myth of Human Genetics website goes into instances where assumed single-gene heredity for non-disease traits like physical appearance and behavior may oversimplify genetic complexity.
Historically, traits such as height, skin color, and intelligence were believed to follow simple Mendelian inheritance, controlled by a single gene. Yet, modern research has revealed the complex nature of polygenic inheritance, where multiple genes contribute to a phenotype. For example, height is influenced by the combined effects of numerous genes, each contributing minimally to the overall trait.
In conclusion, while Mendelian genetics provides a useful framework for understanding the inheritance of single gene disorders, it’s essential to recognize the complexity of human traits that may not follow simple Mendelian patterns. Many non-disease traits are influenced by polygenic inheritance and environmental factors, challenging the notion of single gene determinism in human genetics.
