Please write me a section of the discussion part of my thesis, make sure there is no plagiarism please and follow the outline below on what to include and what not to include use of any AI please and no plagiarism or the use of plagiarism checkers, write in scientific writing as well. use included references as well as other relevant references when comparing my results to previously mentioned results they should be open access please and referenced correctly using APA. I also attached the result section to use as reference when writing this section this is how you should divide the words: discussion outline
1. Introduction/Overview (Approx. 600-700 words)
-Restate the research aim and objectives in detail.
-Provide a brief overview of the context, highlighting why studying miRNA125b-5p and its role in microglial activity in SMA is important.
-Mention the main research questions or hypotheses, emphasizing the broader implications of your work.
2. Detailed Interpretation of Key Findings (Approx. 1200-1300 words)
-Discuss each major finding in depth. Break it down into subthemes:
-The impact of blocking miRNA125b-5p using ASO (antisence oligonucleotide )on microglial activation ie; Nfkb1 pathway by releasing Tnf-a.
-How microglial activity modulates neuroinflammation specifically in SMA.
-Compare and contrast your findings with existing literature (include multiple studies, theoretical models, and conflicting evidence).
-Offer in-depth analysis of any unexpected results, providing hypotheses and linking them back to relevant biological mechanisms.
