First page (chapter 16: epidemiology) :
Go on the CDC or WHO website and select a pathogen, give the following information for your selected pathogen, include a picture/image of the pathogen as well:
1. Geographical distribution of pathogen (global distribution of pathogen)
2. Very brief summary of signs, symptoms, transmission of infection/disease
3. Number of cases/infections over the last 5 years (give the number for each year)*
4. Number of deaths from this infection over last 5 years (give the number for each year)*
*You can create a table showing the number of cases and deaths from the year 2017-2022, if data is not available for the last 5 years, give the most current data available
5. Is this infection classified as a sporadic, endemic, epidemic, or a pandemic disease?
6. Over the past 5 years, have the number of cases per year been increasing or decreasing? Why do suspect that this is happening?
7. Over the past 5 years, have the number of deaths per year been increasing or decreasing? Why do suspect that this is happening?
Please find a pathogen that is tracked/reported by either the CDC/WHO. There must be data available for the selected pathogen. The pathogen can be from our 80 pathogen list.
Second page (Chapter 17: Non-Specific Defenses):
Part I
A. Explain first line defenses of the immune system.
B. List at least 3 different features (chemical or physical) that protect against pathogens. Where are these located? What is their role in protecting and fighting off microbes?
C. Pick 1 first line defense and explain what would happen if it is not working properly
Part II
D. Explain second line defense of the immune system.
E. List at least 3 different features (systems, cells, chemical messengers) that work together to protect against pathogens. Where are these located? What is their role in protecting and fighting off microbes?
F. Pick 1 second line defense and explain what would happen if it is not working properly
Third page (Chapter 18 : Adaptive Immunity)
Part I
Compare and contrast cellular and humoral immunity. You must give at least 3 similarities and 3 differences. Think about the types of cells involved, where they are derived from, the function of each type of immunity, the chemical messengers needed, the types of receptors, how each immunity is activated, You may use a table (see example below)
Briefly explain how cellular and humoral immunity work together to neutralize a pathogen, such as COVID-19, once you are exposed and infected by it.
cellular immunity vs humoral immunity Similarities Differences
both use lymphocytes lymphocytes originate in different organs
Part II
1. What would happen if a person was born without humoral immunity?
2. What if a person was born without cellular immunity?
Explain these questions in terms of effects on the person’s immunity and disease/infections. Use specific aspects of each immunity to answer these questions such as cells and molecules affected
Fourth page (Chapter 19: Immune System Diseases) :
Pick either 1 autoimmune disease or 1 immunodeficiency disease not mentioned in the lecture or textbook and give the following information for the selected disease:
1. molecular cause (location on the chromosome, mutation etc)
2. signs and symptoms of disease (clinical features)
3. pathogenesis
4. number of people affected with disease
Use the following link to help you pick a disease: https://www.ncbi.nlm.nih.gov/omim Links to an external site.
Fifth page (Chapter 20: Practical Applications)
Discuss 1 serological test and 1 molecular tests that help diagnose a patient with the correct pathogen. Give a brief summary of each technique or test and explain how each allow for correct diagnosis. How accurate is each? Can they give false positives?
What type of testing is being done on suspected COVID patients ( 2 different types of testing)? How accurate are they?
