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Explain, using your knowledge of hypercoagulability, why the trip to Australia contributed to Leona’s DVT

October 10, 2022
Christopher R. Teeple

Leona is 52 years old and smokes. She is also overweight and has atherosclerosis. When she was given a 2-week vacation from work, she packed up her bags and flew from Minnesota to Sydney, Australia, for the trip she always wanted to take. Unfortunately, just 3 days after she arrived, she was hospitalized when her left calf became inflamed, causing her considerable pain. The physician attending to her told her she developed a deep vein thrombosis .

***Respond to the following questions regarding Case Study 22. Your responses should be in complete sentences and paragraph form. Do not repeat the question, just label your responses with the appropriate number.***

1) Explain, using your knowledge of hypercoagulability, why the trip to Australia contributed to Leona’s DVT? Why was Leona already at risk for thrombus development?

2) How does Leona’s atherosclerosis affect platelet function? Conversely, what is the effect of increased platelet activity on the development of atherosclerosis?

3) How do atherosclerosis and immobility promote changes in blood coagulation?

When Leona was in hospital, she received heparin therapy. Explain why this course of action was taken to treat her DVT. Why was she not given heparin tablets to take back to the hotel with her?

Worth 25 points. Refer to the Case Study Rubric for grading criteria. Your responses will be evaluated for appropriate writing style and depth of discussion. Avoid brief Q & A responses. Your analysis will be in essay format, and there is no need to repeat the discussion questions in your response. Submit your case analysis in the text box provided or as a file upload. Be sure to review the rubric for grading criteria to make sure that you are covering the analysis in the depth expected. Your case analysis should include the following:

The title of the case
Your responses and discussion of the questions posed. Be sure to go beyond briefly answering the questions. Each prompt should be discussed in a separate paragraph.
Include in text citations for each response paragraph.
Include a textbook and chapter reference at the end of your case analyiss.

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