To Prepare
Review of the Resources for this module and consider the impact of potential pharmacotherapeutics for cardiovascular disorders introduced in the media piece. Review the case study assigned by your Instructor for this Assignment. Select one of the following factors: genetics, gender, ethnicity, age, or behavior factors. Reflect on how the factor you selected might influence the patient’s pharmacokinetic and pharmacodynamic processes. Consider how changes in pharmacokinetics and pharmacodynamics might impact the patient’s recommended drug therapy. Think about how you might improve the patient’s drug therapy plan based on the pharmacokinetic and pharmacodynamic changes. Reflect on whether you would modify the current drug treatment or provide an alternative treatment option for the patient.
By Day 7 of Week 2 Write a 2- to 3-page paper that addresses the following:
Explain how the factor you selected might influence the pharmacokinetic and pharmacodynamic processes in the patient from the case study you were assigned.
Describe how changes in the processes might impact the patient’s recommended drug therapy. Be specific and provide examples. Explain how you might improve the patient’s drug therapy plan and explain why you would make these recommended improvements.
Case Study 1 LM is an 86-year-old female admitted to the emergency department with delirium. Her spouse is with her and verifies that LM adheres to the medications she is currently prescribed. She does not self-monitor her BP or heart rate at home.
PMH: A-Fib diagnosed 1 month ago HTN x 10 years CKD x 5 years Osteoarthritis x 7 years GERD x 20 years
Medications: Digoxin 0.25 mg QD Metoprolol XL 25mg QD Warfarin 3 mg QD APAP 650 mg TID Omeprazole 20mg QD Multivitamin QD Allergies: NKDA
Social History: Married to husband for 57 years No smoking, alcohol, limited daily exercise (short walks each morning)
Family History: None reported Vitals: Labs: Wt 113 lbs Ht 5’4” Na+ 138 K+ 4.0 BP 101/58, HR 52 Cl- 99 CO2 27 BUN 33 Cr 1.2 Gluc 109 INR 3.8 Dig 2.4
PE: Elderly female with altered level of consciousness, no signs of bruising, bleeding, or other injuries.
