1.)You have a sample of a population where you know that the percentage of the homozygous recessive genotype (aa) is 24%. Using that 24%, calculate the following:
A. The frequency of the “aa” genotype.
B. The frequency of the “a” allele.
C. The frequency of the “A” allele.
D. The frequencies of the genotypes “AA” and “Aa.”
2.)A rather large population of Biology instructors have 393 red-sided individuals and 557 tan-sided individuals. Assume that red is totally recessive. Please calculate the following:
A. The allele frequencies of each allele.
B. The expected genotype frequencies.
C. The number of heterozygous individuals that you would predict to be in this population.
3.)Cystic fibrosis is a recessive condition that affects about 1 in 2,000 babies in the Caucasian population of the United States. Please calculate the following.
A. The frequency of the recessive allele in the population.
B. The frequency of the dominant allele in the population.
C. The percentage of heterozygous individuals (carriers) in the population.
4.)Within Guinea pigs some produce a rosette (swirling) coat which is controlled by the dominant allele “R” and the recessive allele “r” controls the smooth coat. If there is a population of 750 guinea pigs and 150 have a smooth coat estimate the allele frequencies of this group of guinea pigs.
5.)In certain African countries 4% of the newborn babies have sickle-cell anemia, which is a recessive trait. Out of a random population of 2,000 newborn babies, how many babies would you expect for each of the three possible genotypes
6.)In Eastern Pennsylvania many Amish communities thrive. The syndrome known as Ellis-van Creveld syndrome (a form of dwarfism) is prevalent among the Amish. Symptoms include short stature and polydactyly (extra fingers and toes on limbs). The Amish population stem from a small number of German immigrants who settled there. They tend to marry within the group. Consider whether this is an example of the founder effect or bottleneck effect.
